Mitochondrial Behavior
With Dr. Jodi Nunnari
How the cell’s powerhouse is built.
From the lab of Dr. Jodi Nunnari
Fascinated by the role of mitochondria in human evolution, Dr. Jodi Nunnari has studied this organelle for her entire career. Today her research is focused on how mitochondrial behavior is controlled within cells.
In addition to producing ATP and contributing to cellular stress responses, mitochondrial functions influence an organism’s physiology by regulating communication between cells and tissues. Recently mitochondrial dysfunction has emerged as a crucial factor in some neurodegenerative and metabolic disorders.
Dr. Nunnari’s lab examines the range of physiological functions of mitochondrial division and fusion, how the structure is established within cells and how the genome is organized within the organelle.
Mitochondrial Nucleoids in mammalian cells over time
Time-lapse max projection image showing U2OS cells labeling mitochondria (red), mtDNA polymerase (cyan), and mtDNA (yellow).
Mitochondrial Nucleoids in mammalian cells
Max projection image showing U2OS cells labeling mitochondria (blue), mtDNA (red), and mtDNA helicase (green).
Mammalian Mitochondrial DNA
Max projection image showing U2OS cells labeling mitochondria (green) and mtDNA (red).
“Investigations that further the greater good make me happy.”
Dr. Jodi Nunnari is a pioneer in mitochondrial biology. She was the first to decipher the mechanisms responsible for mitochondrial division and fusion, and her lab at UC Davis is dedicated to studying how the behavior of mitochondria is controlled in the cells.
Experience more breakthroughs and download Dr. Jodi Nunnari’s full research report.
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